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# Tropheryma whipplei TW08/27, TW08/27

>TW701 ribonucleotide-diphosphate reductase small chain
MGILGTGIQDGLLLKPVRYQWAMDLYEQAVANTWFPNEIQLGEDIADFKK
MTHEEKHAVTFLMSYFNPNELLVNKALAFGVYPYINAPECHLYLAKQMWE
EANHCMSFEYVLETFPIDREEAYSSHIEVPSMARKEEFEVEYIRRMTEET
LDITTTEGKRDFIRNLVAYNVVLEGIWFYSGFMAALYFRQRNLLRNFGSL
IDWIVRDESLHLKFGINLILTVLEENPDLQTSDFADEIRGMIIAGVEMEE
EYNHDLLPNGILGLNSGYINQYVKYLADRRLEELGFDPEYNVTNPAKWMA
TANDTFELVNFFEAINTSYESNARSLS
>TW714 putative nucleotide kinase
MFVTFEGIDGSGKTAQLTAAGEFLKASGKQVVLTREPGTISCIRDYVLAS
DMDIRTEALLYSADRAENIAKNVIPALNAGKVVLQDRYLDSFLAYQLADN
KLVETDIMRLFEFSSQGLRPDLTLLFDLTPACAQERLENRDRIERKPIDF
HSKVRNIYLKLSADNTDRIRVIDASQSFSKIHQQVIYHIERKLGGTHSA
>TW490 conserved hypothetical protein
MTSVFTRIINREVPAEILFEDDEFICIEDIAPKAKIHYLVIAKHPWKDVT
EAVRDDPLFVNKILAIAVRLTKDFGSQFRLIFNTGALVGQTVFHVHAHIL
SGEALGE
>TW702 ribonucleotide-diphosphate reductase large chain
MSLTVVKRDGRKQQYDSRKVCAAIEEALSGSSDAITEQLSSELELTLFDG
ITTSQLDESLIQVALQNVKDDPVYDRVATRLLLKSIYRSVLGEYKNCCQL
RDLHVKHFRGFIEKGVEEGILDRRLDGRFDYDRLSRALDPQRDTLFKYIG
LVTLNNRYGIRARSGKNLEVPQYLWMRISMGLSVLEKDPTGSALKFYEKM
SKLEYLAAGSTLVNAGTCTPQLSNCFVMEMQDDIEHIAKTTRDVMLLTKG
TGGIGLSVTKLRAQGSPIRSNNTRSTGPIPFMHTIDSVLRAVSRGGKKFG
ALCFYMENWHMDFPEFIDLRQNSGDPYRRTRTANTAVWISDEFMKRVIND
REWYLFDPLETPDLNELYGAEFSKRYEYYVNQAEAGRLSMFKKLGAREQF
RAILMSLQTTSHPWITFKDTINLRALNNNTGTIHLSNLCTEICLPQDREN
VSVCNLASINLSRHLIDGEIDWQLLEESTRLAVRQLDNLIDITCSSVKES
DNSNNLNRAIGLGIMGFTNLIERLGYSYESEQAFDLIDRLMEQISFVAID
ESCNLAEERGPYKNFHGSRWSKGMLPIDSIKIVSQNRGVPVSVNTSYRLD
WDSLRKRVRNGIRNATLLAIAPTASIGLVAGTTPGLDPQFSQIFSRSTSF
GKFLEVNENLVLDLKRRGLWERVREDILRSQGNIQQIDAIPGEIKANYKT
SFQLSPYAFVQVAARAQKWVDQAISRNMYLESRDISDMVSVYTTAWEMGL
KTTYYLHMKPRHQAEQSTVKVNKRTEGGNRRGFAGFSKNKDV
>TW763 conserved hypothetical protein (putative deaminase)
MEHTVKITGEHKDLYRGSFRDTPDEKIMRKALCLAHAAGEKGEIPVGAVI
ADVNGKTIAEGFNKREESKDPTDHAEIIAIRKASQMLKDWRLSGLTLFVT
MEPCTMCAGAIVTSRISRVVFGAFNNKTGSVGSRIDILRDEILNTNIEVV
SGVLISECEGVLAKFFADLR
>TW061 putative GTP-binding protein
MDFTSIVAIDGPAGSGKSSVGRAVAQYLGYGFLPTGSYYRAFAFLLDQTK
DLDSQLDSFISSVRNDLDPYNSGFNVHIDDSPFFGSSGISASSRNIASEL
NNPEITSKTAAVARNKSVRVRLNEYFRKLCSESIYPAIVLEGRDATTVIA
PNARVKIFLTASLVKRAARRSEQLSSEPPNSVLEALRQRDEADNAVTDFL
SDDSSRITLDTSDLTFSESVARVLEVIEQAGMPFVSDKWVGENADVLAAS
GELGATVVIVGRPNVGKSALVNCILGRREAVVENRPGVTRDRVVYPAFWA
GRPFTLVDTGGWECDAEGLDAEVVAQAEIGMSIADIIIFVVDVQHGPVST
DAVIARNLQRQNKPIFLVANKADNASSDSDVAQFWSLGLGQPYACSATHG
RGVADLMDIVMQSAQVHTPSFCSGAPRVALIGRPNVGKSSLINQLTNSRR
AIVDDLAGTTRDPLDALAVIGDKSWLFVDTAGLRRKFKSQKGADFYAYLR
ATTVLRRTEIALLLLDASHAITEQDVRIAEMVVESGRALVIAINKWDLLD
EERRYWLEREIDNTFFRFAWAPRVNISARTGRGVKQLATALQTALTNWNT
RLNTARVNHFLQRITREQPHPTRGGRRPRILFASQTGVAPPTFTLFTTGF
LEPTYRRFLQKSIRSQHSFTGSPIILSVKIRASRNR
>TW633 conserved hypothetical protein
MFFVMDPVFLSEITVELVKHSASDSDVVFSARVSTLGSFVAVTDCLSNRD
IGLITFLMRERHGSPFEHSHMTFRISAPIFVFREFMRHRIASYNEESGRY
KNLDPVFYIPDEKRKLVQIGAPGAYKFEEGTSEQYGLLIEEMKELSLAAY
DTYKRLLACGIAREVARMILPLNLYSTMYVTINARSLMNFLSVRTSRANS
AFHSYPQREIELCADRIEEIWKGLMPETHAAFEKQGRVAP
>TW639 conserved hypothetical protein
MEIVFVSENENKITEAREILLPLGFQPIFCGVTCRETGLTFTENAVLKAQ
AAVGSVKDVPIMADDSGICVDALNGMPGVLSSRWSQDGRNIDLLLWQMRD
VPDVHRTAHFVCSIACVMPNTEVRTVSSVWHGRILHVPDGTGGFGYDPVF
LPDGYSVSAAGLGSDLKNRISHRYKALRLMSSLLKRTYSSCHA
>TW806 conserved hypothetical protein
MKIIIDVMPKPGLLDPQGRAIASVLTERGWDNSTRIRVGKRFELCVDPVS
ETCELDFIRDLANDLLINPVIEDVVDIRIEDD
>TW095 putative integral membrane protein
MKSMNKKLAVFLLARDLSFVLSATILEVWCLSSVTWPVNAIFGVVLPIVL
GLGWACILSTSPAISASIYLRSIVYLVVSLLAALSLIDFRSIGLAVAHLV
LASFIGFVLVLLD
>TW449 conserved hypothetical protein
MIDVLDHFATTVIDSARSYGPCHDAIEDMVGQDDGDGLAHYARKGEITRS
YVMGIPVIALCGKRWLPSRLPDKLPICQTCSDIYNSLSD
>TW507 conserved hypothetical protein
MQEGSSDFAGIPDGYKRLWTPHRVVYLEGARHDGNPETCPFCSAYRKTDE
EGLIVYRGDLSYVVMNLYPYNSGHTLVCPYRHIATYDLASSDEILEMGLL
LQKAILVSKRVLGCEGFNIGINQGRVAGAGIAGHLHQHIVPRWAFDSNFF
PIIARTKALPKLIEQVRCDLQRGWDDLV
>TW226 adk, adenylate kinase
MRAIMVGPPGSGKGTQCGLIQSRLGISVIATGDVFRERMKTDMALRDIVS
SGGYVSDSTTNRIVEDCLDKEDVSSGFVLDGYPRTLQQLDFLEGFLKRRA
LTLDAVFSLEVATDLLIERLRARSKESGRTDDRDSVIARRLEIYTEMTLP
IIDACEEKGLLHRIDASKGIEEVFQSIKDVFDRVTI
>TW403 carA, carbamoyl-phosphate synthase small chain
MLSFRSAVFVMEDGSCFEGVPFGAVGTAFGEAVFSTCMTGYQEVFTDPSY
TAQILVMTAVHVGNTGINDFDNESDRMWPSGVVIRDPSPIASSFLAKMDL
AKALASEGVIGISEVDTRAIVRKLRTSGAMRAGIFSQPDRPLPDLVDQIR
GTQSMHMRSLTSEVSTTSRRFISSESHFATLLVLDLGVKKSTINLLLEQG
FDIWLMPHNISFDEAMQIKPDAIFYSNGPGDPAASGTQVDLLRSLLRAGL
PYFGICFGNQLLARALGFETKKLLFGHRGINQPVFNRATKQVEITSQNHG
FSVDMPIDRISVSPLNFGRVEVSHYCLNDYEVEGIRCLDIPAMSVQYHPE
SCAGPHDSRYLFREFRRMVEGHLERRYNAEP
>TW404 carB, carbamoyl-phosphate synthase large chain
MPNPRDIGSVLVIGSGPITIGQACEFDYSGTQACRVLKEEGIRVILLNSN
PATIMTDPEFSDATYIEPMTIEVLEAILDKERPDAVLPTLGGQTALNLAM
QLHNKGLLEKYGTQLIGATPEVIARGENREMFRHIVLSSGAEVATSEVIT
SVEGAVLFAQKNGYPLVIRPSYTMGGLGSSLVHTESELVDSVKQGIEASP
NGQVLLEESIVGWKEYELELMRDVAGNTVIVCSIENIDPVGVHTGDSVTV
APAMTLTDREYQNLRNIAIAIIRMIGINTGGCNIQFAVNPTDGRVVVIEV
NPRVSRSSALASKATGFPIAKLAAKLALGYRLHEIKNDITKKTFASFEPS
LDYVAVKIPLFAFEKFPKANPELTTSMKSVGEVMAIGRNFTTALQKAMRS
LDQPHMCFHWQPFESPGHSIASDVPDPREYYLDFIRTPLPSRLVAIQQAL
RFGASIDEVHEASRIDKWFVSQIDLINKTADSLKDLSMDCLSRAKRHGFS
DRQIADLLRIDEEDVRKRRSALGIAPVYKTVDTCAGEFPAVTPYYYSSYD
SENEAIPSPSRKVIIIGSGPNRIGQGIEFDYSCVHAAMALSGMGIETVMI
NCNPETVSTDYDTSDRLYFEPLTLEDVLEVISVEQRNGDLLGVIAQLGGQ
IPLSLAKSIQHEGIPILGTSPESIDLAENRDLFSNLLRSLNLPTYEHRTV
SNKDEAIIAANKMGFPVLLRPSFVLGGRGMKVIHDSQALEDYFNTFHAVD
SEHPLLIDKFLSDAIEVDVDALYDKHELFIGGIMEHIEEAGIHSGDSSCT
IPPVTLGKNIVNQIVSTTHAIARTLSVLGPVNIQFAIASGILYVLEANPR
SSRTLPFVSKATGIPLAKAATRIMLGHTIEDLQREGLLPQRDMRFFNPTD
PIAVKEVILPFKRFRTKSGEFLDTLLGPEMQSTGEVMGIGPTFPIAFAKS
QQAAFSELPRTGAIFVSVADHDKRKVVLPAMRFYKLGFKIFATSGTADTL
RRFGIDVVTIQKFSEAKKTSSRSVVDLIREGRISLVINTPSGGVSIADGY
EIRVTALACEIPVFTTISEMNAAVISLESGSHEIASLQELYSSRARSAEN
LCG
>TW796 dcd, deoxycytidine triphosphate deaminase
MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAY
IDPAEPQEALTRLVEVAENQAFVLHPGEFILGSTCETVSLSNDLAARLEG
KSSLGRLGLLTHSTAGFIDPGFSGQITLELGNVATLPIKLWPGMKIGQLC
FFQLSSPAKNAYGSPVCASRYQGQRGPTASLSHQHFYRARFTEIGL
>TW485 dgt, deoxyguanosinetriphosphate triphosphohydrolase
MTLLTCKTFRARCSYTSHMKQFTYNDFDRERLYPEKTENIRDSFTRDRAR
VVHAAYMRRLADKTQVYSPLLHLTTVRNRLTHSVEVAQIGMDIAHLIGVN
QNIVDTACLAHDIGHPPFGHNGERVLNKWACGIGGFEGNAQTFRVITRLE
PKVYAPDTRRSFGLNLTRASLNAVCKYPWSLKDARRFCIATKETTGLQNL
LCDCDAVHKFGFYEEDRETFSWVRKLSRAHILSIEAQIMDFADDVAYSVH
DFEDSLLLERNLHSVLRSQNLPHQIQRFMTETFSCEIADKADEAFSNLSE
MWRDLSRNIAFGSLHNKYLTGISMRGFLARLKNLTSNLIGRFAYAAIERT
RESLVERDRSDAQLVVPNTTLAEIALLKSMVFVCVMQKRKQFYVLQAKAL
LRLVEKIWELACKDAYALDDLFREDWELAKCEAEKRRVVLDQIASLTDLD
ALLLMQRYCSESDAVREFLMKSESARSQL
>TW277 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MTVEVLFKGGYTPQRAFDGDAGFDLQSSHTAVIQPRCRQVVKTGIAIALP
DGYAGFIMPRSGLASENGITLVNSPGVIDAGYRGEISVVLINTDLHQAFH
ISQGDRIAQLVIMPVCHASFIEVDTLPGSARGISAFGSSGRHDTRG
>TW406 gmk, guanylate kinase
MQLFDLWTDLLDLLTIVAGPTAVGKGTVISHLRKCHPQVKVSISATTREP
RDSERDGIDYYFVTDEVFDCMVRSGQMLEWATVHGLHKYGTPKEEVERLL
HTGQPVILEIDLQGMRKVRKILPAVRTVILLPPAWDDLICRIKRRGSESQ
DEIDARLATAKKELEAIGEFDYKIVNADVEIAANELWLAMNRV
>TW089 guaA, GMP synthase [glutamine-hydrolyzing]
MRPVLVVDFGSQYSQLVVRAIRECGYYAEFASPSISAAECLALSPIAIFL
SGGPASAYKDNAPKLDEEIFNCGIPIFGICYGFQLLAQAFGGSVKKANAP
EYGPADITIVNKAFFSGQPDRQTVWMSHGDSVIRAPKNFCILSTSQDAVL
SFCNRDRTIAGVQWHPEVKHSRFGKHTIKAFLSSFAAPNWDPEQTICGTV
DSIRKTVGCKRVLCALSGGVDSVVAATLTHRAIGDRLRCVFVDHGLLRLN
EREQVEEYCSSLGLNVSTYDASDCFLSALSGIRDSEQKRKVIGREFIACF
SKLQERFDIKPHFLLQGTLYPDLVESGATPGGATIKSHHNVGGLSDNLGF
ELLEPLKYLFKDEVRKIGLQLGIPKHIVHRQPFPGPGLAIRIIGEVTNKK
LSILRAADAIVRHELRDWTDIWQCPVILLSDVQSVGVRGDSRSCGFPIVI
RPVSSDDAMTADWYRLPYDVLARISGRITNEIPEIVRVVLDITPKPPATI
EWE
>TW086 guaB2, putative inosine-5'-monophosphate dehydrogenase
MEVGFSRNARRAFSLDEVAVVPSRRTRHSSEVSIEWKMDAFSFDTPIISS
PADSVVSPSTIVELSEFGCLGILDLEGVWTRYENPEPVLREISALPEEKA
CLGLQKIYSEPIKRHLLERRLQELRDAGVIVAGCLSPQTTNALYKSVISA
GVDIFVIRGGTVSAEHVSKSDNVLNLKRFIYELDVPVMVGGVATYTAALH
MMRTGAAGVLVGFGGCAGSTNHASLGIKVPMATAIADVAAARKDYLDESG
GRYVQVIADGSMNTSGMAVNALALGADAVMMGTPLVRSTTSPGFGYHWGR
EAHHMTLPRGRRAYIGQTASLQEIIQGPGHSPDGTVNFAGAIRRAVALAG
FQDLKNFQRVEMVVIQDQRRCCA
>TW172 hpt, hypoxanthine phosphoribosyltransferase
MKPLLSEAVIHRRLAQLALQIDEDYRGTSIVLLGVLKGSIMLMADLSRLL
SSDLRIEWVTLSSYGNDTVSSGSIRIVHDLDADIRDRHVLIIEDIVDSGL
TLGWLLAKMRERRPASIEACVLLRKPHARGTDVRYLGFDIPDEFVIGYGM
DYAEKYRNLKSVYVLEQ
>TW290 ndk, nucleoside diphosphate kinase
MEQTLVIIKPDGIRRGLIGQVLSRIEAKGYQIVDIRMLVPDRQSVEEHYL
EHRDRHFYLPLVDFMTSGPIVLVRAEGHGVVDALRTLVGVSDPTLALPGT
IRGDFGRNWGLDVIQNIVHASDSVKSAKRELDIWFP
>TW585 prsA, ribose-phosphate pyrophosphokinase
MTDLLSCAPHARGANNRPGFSDRDVQNDGPMRNLVLIAGRSHPDLARATA
ESLGVGLLQTDIRTFANGEIYTRFNSSVRGKDVFVLQTGCDPVNDGLVEL
LLLIDSCKRASAKHISAVTPCYPYSRQDRKGYGREPISARLVADLIACAG
ADRIITVDLHASQIQGFFNGPVDHLTGVPALIKHVKSLRIDNLTIVSPDI
GRVKVADVWSDKLNAPLAIIHKRRDPRVHNNVTMHEIVGDVRSRVCLVVD
DLIDTGDTLAKAAIALKKAGAVKVIAAATHGIFSTPERLVSCGEIDHVIV
TDSVPASKVFDRVKTVSIAPLLACAICEVVTEGSISEMLDCVSKRIDN
>TW018 punA, purine nucleoside phosphorylase
MEDICNTELTAATLAAKQIADITGIARHDIAVTLGSGWVDAVSNLGELIT
TIPAQDIHGFFPPVLAGHSGVLTSIRLTCGVYVLVIGARTHLYQGHGPEA
VVHGIKTAHAAGARVAILTNGAGSTVPDWGPGEVVVIKDHINLTGKSPLS
GANFCDMSDIYTAALRQKILQMAPNIPQGVYAQMPGPQYETPAEVKMLRT
IGADLVGMSTALEAIMAKSLKMNVVGLSLVTNLAAGIGTGQLSHDEVLTV
SEQARQKTSAFLVELIRDIGQDLSGRK
>TW801 purA, adenylosuccinate synthetase
MPATILIGAQWGDEGKGKATDLLAKDIDYVVKFNGGNNAGHTVVIGGDKY
VLHLLPSGILNENVVPVIANGVVINPEVLFDEIATLNSRGVNTDKLVISA
NAHIIAPFHRTIDLVTERFLGKRQLGTTGRGIGPTYADKINRIGIRVQDL
FDKSVLRQKIEGSLSNKNHMLVKVFNRRSVSVTEMLDYLLSFAERMRPMI
ADTSLLLNNALDCGKHVLFEGGQATMLDVDHGSYPFVTSSNATVGGAITG
AGIGPTRVNKVIGVAKSYTTRVGAGPFPTELHDEYGEWLQKRGYEVGATT
GRKRRCGWFDGVVARYATRINGITDYVLTKLDVLTGLDRIPICVGYKVGD
SVFREMPVSQSDFHHAVPIYEDLPGWQCNISECESFDSLPPEARGYVLAL
EDLIKARISVIGTGPERENIIIRHPLGIF
>TW800 purB, adenylosuccinate lyase
MSEDEYDSLSPLDGRYGPAVRALRGFLSESALIRERIRVEIGWVFFLWRK
AVFGLAEPTKEDERFLSSIVHDAHKNIPRVKKIEERIQHDVKAVEIFLRE
RFTQQGLGNIVELLHFACTSEDINNLAYALNMKAALSEVILPSIDELIGH
LEKMSQKYAGDAMLARTHGQPATPTTLGKELLVFVYRLKRQRKNLEDVQF
LGKFSGATGTFSAHCVAAPNYPWQEWAKEFVNSFGLIYNPITTQIEPHDW
QCELLERVGHICRILHNLATDMWSYISFGYFQQGFISESVGSSTMPHKVN
PIRFENAEANLEMACGIISCIVASLSTSRLQRDLSDSSVQRNIGVALGHS
LVAIDNLKRGLAGIRLNKNRLTEDLNNNWEVIAEAVQTTIRAEILACKSN
EANPYERLKDFTRNKKITKHTLDEFITNLDLSEHAKKRLLELTPSKYTGL
AERMVQAHSSGTGGTKNSIGTGGTKNSSGAG
>TW119 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MTRKLEIPESRDLPDWSHIGGGKVRELYVHRQYKNILLMFASNRVSAFDF
VLEPEIPEKGRMLTQMSNWWFRKLPAENHLLENYDQELYRDLASHIPSHI
LERSTICRKMDIIPFEFVIRGYLTGSAWADYLENNTVYGIKLKGKFRQGD
RLPGPIFTPTTKSRTKDTPVRYEDLVNAIGLSHAQQLREMCTDYYTTAEQ
IARNKGLIIADAKFEFGIAEGKAYLADELLTADSARYWDINSWGQFDLPI
ERRLDSFDKQAVRDWVKCNSGKNITPQNITPLRLPQELIQTVYKKYKTLL
AKLTG
>TW739 purD, phosphoribosylamine--glycine ligase
MKILVIGSGAREHAIAAAIDSEGPHEVCVSPGNAGIAQTINCVQTTSDAD
LISIAKNFDLVVIGPEGPLAGGLVDRLKSSGATVFGPSQAAARIETSKHF
AKEIMANANVRTAKSVLVNNVDDLSRALKASSRPYVVKADGIAAGKGAIV
TGDRDAAYRHGSYWIRKGPVLLEEYVKGREVSLFFLCDGRVLVPLSPAKD
YKRLGESDTGPNTGGMGSHSPVTDLPANFVEEVQEAIAYPVIKQMAACGI
VFRGLLYCGLALCDDGPKVIEFNARFGDPETQVILPRLTSSLSELLYATA
KGDLRNISKPSFNNKAAVCVVIASGGYPEIPAGDTPIIGLNGTGDVQVLF
AGARRNYPDEPDILHSHGGRIMNIVSLDKTFAKAREKAYRAVDQISITNK
QFRRDIALEEEFMETNPLG
>TW029 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit PurE
MTGKNINDEGSKCPALVWLLMGSDSDWPVMSGAADILQQMNISFRVNVVS
AHRQPEKMISCAKRARDMGFKVLIAAAGGAAHLPGMLASVTTLPVIGVPV
GQKNLSGLDSLLSIVQMPSGVPVACVGIDSAKNAALLAARILGVQSADIE
ASRIADSLSAYQQSLFDQSNEKDRMINEPK
>TW737 purF, amidophosphoribosyltransferase
MCGIVGLIGSEPANQAIYDSLLLLQHRGQDSTGIATDESGILHLRKARGY
VREAFRTRHMRSLLGRVGLGHVRYATQGSVSSEEEAQPFYVNAPYGIAMV
HNGNLTNARKLSKELFHTDRRHLNTSSDTEVLINVFANELQQSVSGFELS
PDQIFSAVSRVHKRVEGSYAVVALIAGTGILAFRDPFGIRPLVLGARESK
FTSNTEWIIASESVVLEAQGYKLLRDFAPGEAVFITQQGEIFMTQCAQNP
QLNPCAFEYVYLARPDSVMNGVSVYEARLRLGDTLSTTIKQQMPCGNIDV
VMPIPDSSRPAALQVSRNLGIEYREGFLKNRYVGRTFIMPGQLQRKKSVR
QKLNAMGLEFRGKNVLIVDDSIVRGTTSKEIIHMARSAGANQVFFTSAAP
PVRYQNVFGINMPTSSELVAHNRQLQEIRQYIDADRLIYQSIEDMRRAIM
HGGEFKRLEDSCFSGEYVTGRVTQEYLDWVENTQSS
>TW094 purH, bifunctional purine biosynthesis protein PurH
MTTNIRIKRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIP
VRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQLQQLGVDAF
DLVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHTRVVVIV
DPSDYIHVINSLERGAPSRLRHQLAIKAYSHTSEYDLHISRWLSERFYKH
TLYSSSDSVGDVCDNNLDSNDHFVELRGKKLGDLRYGENSHQKASLYLSC
KESVPQLGLASAALLGGKQMSYNNYLDADVASRIVNSFDLPTVSFVKHGN
PCGIASNIEVAIACRNAHECDPTSAFGGVVAVNREVTLDVATHLLPIFIE
VVVAPGYDPQALQLLLKKKNLRVVELPECASYPQDQLRQISGGFLVQDAD
KFDHHDTFSSWTQVSGPRIFMDAGADNETLMDLEFAWKSCAFVKSNAILL
AKNMASVGIGMGQVNRLDACYLAVNRAGSRSLGAVAASDAFFPFSDGLDV
LINSGVKAIVQPGGSVRDNAVIAAAQQAGVTMFFTGKRHFAH
>TW028 purK, phosphoribosylaminoimidazole carboxylase ATPase subunit PurK
MLSIARIASPAQYNLRLMFERLSCSVGVIGGGQLARMMIAPAQALGVDLK
VFADTPDSSAALAATAFGSPENGAAVLEFAQTVDIVTFEHELVPADVLQL
LDERGIEMLPCPRALRYAQDKLALRRYLDEISVNQPAWAEVRSEGDLERF
ISEHGGCAVVKTGGYDGRGVQVVTLSSEIDTCRNGGFLAEERIDFVCEVS
QLVARSSIGEICVWPLTQTIQENGICVQTITPALGLSGGNALNQLTTFHD
GRTRTPHAPLHSELITKLQDSAKTIALDIARGLNVVGVMAVEMFITQDGK
LLVNELAMRPHNSGHWSMAASITDQFEQHLRAVLGLPLGATDMSHNCAIM
VNIFNSISPAQYREVMTHWPDAKLHIYKKQPRPGRKIGHVVFAGEDLQQL
AIAAEECRQLLRESHAV
>TW803 purL, phosphoribosylformylglycinamidine synthase II
MNMSLPADRDTAKKPSAQKPSAHAQNATAAVDVTALGLTESEYTQICSLL
KRSPTKSELAIYSVLWSEHCSYKSSRRHLRQLADLTEVTKKHLLVGIGQN
AGVVDIGGGWAAAFKIESHNHPSFIEPFQGAATGIGGIVRDIIAMGAKPV
ALMDSLRFGAASDPDTQRVADGVVSGISFYGNCLGVPNIGGETAFDPVYQ
GNPLVNVLCVGVMRRENIRLANASGPGNLVVLFGAPTGRDGIGGASVLAS
DSFTSDAKANRPAVQIGDPFVEKLLTECCLELYAADLVVAIQDLGAAGIS
CAASELAHNGRVGIRLDLSAVPLRDTTLAPDEILVSESQERMMAIVHPDN
LEAFFEITNRWGISGAVIGEVDNSQYLTVVHEGKTLVRLNPKTLTGPSYN
RPVKKPAYLIRRSAANRLPVTNDPHLLREDILQVISCPNLSDKSVITNQY
DRYVQGNTALCHPDDAGVIRMYKNTGVALSCDGNSRYSYLDPHAGAQLAV
AEAYRNVSVVGATPLAVTNCLNFGNPENPEVMWQFRETCRGLSDACKRLE
IPITGGNVSFYNQTDGKDIFPTPVVGILGIVDNLTQTLTSGWNAPDLFIY
LLGVTRPEFGGSVWADTMYGHIGGVPPKLDLARESRLSNLLVAGAKKRVF
ESAHDLSEGGLIQAIVESCLRHGFGADIALDTIRATSLTEALFSESASRV
LVSCRSQEDLRDLCRRNSYEYTLIGTTRHTGELTISEIGKFTLNELSDAR
QKVTRVLFRG
>TW738 purM, phosphoribosylformylglycinamidine cyclo-ligase
MMDPYAAAGVDIVAGQLAVEAMRHAVEATHNSRVPEGLGGFAGLFDISFL
KRYRSPLLVTSTDGVGTKVVIAQELDKHDTIGQDLVAMVVGDIAVVGGKP
LFMTDYIACGELIPERIAQIVGGVARACQEIDCVLLGGETAEHPEVMARN
QYDLAGAATGVVEASDLLGKDKVKTGDVLIGVASSGLHANGFSLVRKICR
DVSFAEYCPDLQTTWGEALLEPTRMYVNLIRDLIKTGKLHAASHITGGGI
PGNLPRILPEGLGARLHPWPIPDLFKVLCEFGSLSLSEVKNAWNLGIGLI
IVASSTSILEDIDDSWQARLIGEVIDGEAIQWTGSLS
>TW093 purN, phosphoribosylglycinamide formyltransferase
MKTAMRLIVMVSGIGSGLLRLIRACEQKELKAEIVAVGSDRHAPALSHAS
DYGIPFFVSPFKEYSNRDAWGANLLNTVLAYKPDLVVLSGFMRILPSCVV
DALSPNLINTHPSYLPEFPGMNAVEDALRAGVKTTGASVIRVDNGIDTGP
VISQMRVKVYSSDTCQTLHSRIKKVEHLLLCRAIKNIYTEQFILKNLLHN
SVRRPSGKTGDR
>TW805 purQ, phosphoribosylformylglycinamidine synthase I
MVRVGVVTFPGSLDDKQTLRALSFAGCAAVQLWHASDTLSSVDAVILPGG
FSYGDYLRPGALASRSRIMVRIIEAAHQGMPVLGICNGFQLLTESRLLPG
AFVANKASRFVCLEQSLIVENNSTPFTMNFSKNQNVIIPIKNSDGCYFAQ
TEDLDRIENEGRVVLRYAGSNPSGSSRNIAGICNEQGNIVGMMPHPEYAV
EPGFGPPGLHGAPVFSAISSWINNAR
>TW576 pyrB, aspartate carbamoyltransferase
MTAHNTPKVHCVIRQALRGQRIGPRQLAEQIGVDIKQLWSWLEPTWSQTL
DIPQSILHDLEDAIDDTSAFYNTQHLLSIDQINRRSLERLFYVTDMFQPL
ARRQVRCNILNGAVLACLFYEASTRTRFSFSTAFSRMGGAVVTEADMLQS
SSVAKGESTSDTSRVISGYADIVVVRHSELGFAERYASDSLVPVINAGDG
SGEHPTQAILDVYTIESEFLYREKTIDGSCIAIIGDLKHGRTVHSLIKLL
SLYERLTFKIFSITDLELPNDFHDLLSGRGHTLEVCDSLRNAVNAADVIY
ATRVQTERIAQDLTAVTGCRLTREVLDDCKKDVIVLHPLPRDSRPDALDI
GTDLDSYSGFMPFGQANNGVPVRMAIFSEILGITDKIEFADSIPWARRIP
YPQALP
>TW402 pyrC, dihydroorotase
MTRQSFFIKNVTLPGLGARTLFLSGGLIQEIICKDIEEHQFLSTKNTDKA
SCRVIDAEGFIALPGLVDLHTHLRNSRDGSIRDVTSAAIAGGYTTVSSMP
NMHPVQDSPEAVNILKAIAKEDAVCDIRPVGAVTKGLRGNEITDMHSLLD
AGVNIFSDDGNCVYDPGIIHQALSFAGRNNCVIAQHAQDPTLTKSAQGDT
QGPIVAPKSLWPSIAESTIVARDILLARAANARLHVCHVSSQESVYAIAW
GKSLGVQVTAEVTPHHLLFYDSLVMTGDTRFKVNPPLRSKESVECLRDAL
IRGVIDVVATDHAPHRNKSPFWHSAPNGMTGLEFSVSVIQKIFVNSGHLT
WPEVVRIMSNKPAEILGMTPNTVKEGSAANFFLYNPDVTRFVTFDDSLGP
SVNSPYAGMNLPGKVMYTFYEGRLVFEN
>TW532 pyrD, dihydroorotate dehydrogenase
MNFLKCVDPELAHRIAAVALKSGLGMFVPQRFHIHLGTTSMGLYFDTPLG
IAAGFDKFADLVIPLYSLGFGHVEVGTVTLHPQPGNKKPRIHRVMSQKAL
INSMGFNNPGAQKMRENILKVRKSGRRLPIIGVNIGKSKVCPLEESAKDY
VKSFELLADVSDYLVINVSSPNTEGLRTLQSVGNLNKILRSVKPIADRFK
RPVLIKISPDLSNSDVTNIALLVKEFGLAGVVASNTTTKRTGLPNEFSSL
HGGLSGPMLKERSLEMLKILRRDLPKNKFCIISVGGVWDYTDVLERLEYG
ADLVQGYTAFVYNGPYWASNINRDLSRLRS
>TW755 pyrE, orotate phosphoribosyltransferase
MQRILDLRRIYALTVDPRALHGSVWKVDFKVVRQELIRYIKDLALFEGEF
ILSSGQKSSYYIDLRRVSLDCRAAPIIGKVMFDLICDLQDVDAIGGLTMG
ADPIACAIMHYAASVGRSYNAFVVRKQKKTHGLARLIEGPDIRGKRVVIV
EDTSTTGNSPITAARRAEETGATVAAIAVMVDRETGARQAIEKAGYSYYA
ALRVTDILDRGTAD
>TW405 pyrF, orotidine 5'-phosphate decarboxylase
MISFGDRLQNAFTDFGHLCVGIDPHEWILEQWGLPNSPAGAQEFALRILD
LSSEHVGLYKVQVAFYERFGSKGIFALEEVISAIRSTGALVIADGKRGDI
SSTMSGYAKAWLCRDSRLFSDALTVSPYVGLGSFKGSIDIARQNGAGLFF
LAATSEMHAFPIQSAILQDRQGTFGESSGSILSCSDITVASYIFESIGTL
VGNPSDCSSFGVVLSATSDLLSLGIGCNLSEFSRVMPILAPGFGYQGVEL
KDSRKRFGSLISNLIISESRSLLASGPRRFSALVNTRSEELRSLFDDSHE
NAG
>TW110 pyrG, CTP synthetase
MNGIKHIFITGGVVSSIGKGLTAASLGSLLTMRGLKVFIKKLDPYLNVDP
GTMNPLQHGEVFITEDGAETDLDVGHYERFLDVDLDRTANVTTGQVYSKV
ITLERTGRYLGETVQVIPHITDEIKRRIRLAPDDIDVIITEIGGTVGDIE
SQPFIEAARQIRREVGRENCCFIHVSLVPFLESAGEQKTKPTQHSVAILR
AAGIQPDALVLRSDKPISSANQKKIALMCDVSAVVNAVTVPNIYEIPCVL
NQHGLDKFVIKHLDLEAGEIDWSYWDDVLDAIENNRSEIEIAIIGKYTGL
PDAYISVIEALRAGGFESKTKVNIKWVDSDDENLEDQLENINGACIPGGF
GIRGIEGLIKAIRICREREIPTLGICLGMQCMVIEYARHVVGMHGASSTE
FTDDTQWPVVTTMLEQRDILIDDQFGGTMRLGSYRAVLSVGSLAASLYGT
TDIHERHRHRYEVNNGYAQRLVERGLIVSGRNTEQDLIEFIELDRKDHPF
YIGTQAHPECKSRPKRPHPLFKGLVAAALARKEIAEFNSGKTVLQ
>TW320 pyrH, uridylate kinase
MASRRVLLKLSGESFGGGAPLVDPDVVSAIASEIVRVSKTIQIAIVVGGG
NYFRGAELSRRGMARDRADYMGMLGTVINALALQDFLEQAGGDTRVQSAI
SMSQVAELYVPRRAERHLTKGRVVIFAAGAGMPYFSTDTVAVQRALEIKA
DIVLIAKNGVDGVYTDDPQINPNAKKIYKITYREALERGLRVVDSAALGL
CMEHGLPMRVFGMESLRDAVSGLKVGTELSQ