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# Mycobacterium tuberculosis H37Rv, H37Rv

>Rv2293c CONSERVED HYPOTHETICAL PROTEIN
MGAPLRHCLLVAAALSLGCGVAAADPGYVANVIPCEQRTLVLSAFPAEAD
AVLAHTALDANPVVVADRRRYYLGSISGKKVIVAMTGIGLVNATNTTETA
FARFTCASSIAIAAVMFSGVAGGAGRTSIGDVAIPARWTLDNGATFRGVD
PGMLATAQTLSVVLDNINTLGNPVCLCRNVPVVRLNHLGRQPQLFVGGDG
SSSDKNNGQAFPCIPNGGSVFAANPVVHPIAHLAIPVTFSRRRDPG
>Rv1593c CONSERVED HYPOTHETICAL PROTEIN
MAHGSTAHEVLAVVFQVRGVGMSRGAAKPQLNVLLWQRAKEPQRGAWSLP
GGRLRNDEDMTSSVRRQLAEKVDLRELAHLEQLAVFSDPHRLPGIRMIAS
TYLGVVPSPATPELPADTRWHPVSSLPPMAFDHGPMVTHARTRLIAKMSY
TNIGFALAPKEFALSTLRDIYGAALGYQVDATNLQRVLARRRVITQTGTI
AQSGRSGGRPAALYRFTDSQLRVTDEFAALRPPGQL
>Rv1341 CONSERVED HYPOTHETICAL PROTEIN
MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETG
VTFEDNALAKARDAFSATGLASVADDSGLEVAALGGMPGVLSARWSGRYG
DDAANTALLLAQLCDVPDERRGAAFVSACALVSGSGEVVVRGEWPGTIAR
EPRGDGGFGYDPVFVPYGDDRTAAQLSPAEKDAVSHRGRALALLLPALRS
LATG
>Rv2292c HYPOTHETICAL PROTEIN
MNPGFDAVDQETAAAQAVADAHGVPFLGIRGMSDGPGDPLHLPGFPVQFF
VYKQIAANNAARVTEAFLQNWAGV
>Rv3454 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
MAQGLKLGLHIPLWAGYACSTLIIFPLVVYGMKVLSQLQLWTTPLWLILM
AAPFGYLVVSHPDSIGQFFSYAGKDGHGGLSFGSVLLAAGVCLSLIAQIA
EQIDYLRFMPPRTPENANRWWTWTLLAGPGWVAFGATKQIIGLFLAVYLM
ANIPGSSTIANQPVHQFMQIYRTFVPGWLALTLAVILVVLSQIKINVTNA
YSGSLAWTNSFTRLTKHYPGRVVFLGVNLAIALILMEANMFDFLNTILGC
YANCGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAINPVGFGSLLL
AAGLSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRRTH
DGIDLPMYDEHGNPSAAVLTCHVCHQDFERPDMLACQTHGAHVCSLCLST
DKQAEHVLPGLARAHIPGDQVP
>Rv0787 HYPOTHETICAL PROTEIN
MHRPPWLAQLRRRLRIGVQLGSRVVLEQGRQPRDVYVIGVLVGDQDRGQT
GDSLEAVRESTGIEEQAGLTELSEEAGMAEMRELHVYDCALMGAFPMRLI
LATMLVAGRLLATLMAAPSAQAEPETCPPICDQIPATAWISTHAVPLNSQ
YRWPAMAGAAVAVTRATPRFGFEQVCATPAFPHDSRDWAVAGRVTVVHPD
GQWQLQAQVLHWRGDTARGGQIAASVFGTAVAALRACQLGAPLQSPSVTD
DEPTRMAAVISGPVIMYTYLVAHVSSSTISELTLWSSGPPQVPWPTVADS
AVLDALTAPLCEAYIGSCP
>Rv3752c POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADGTELARAVNAREALGDP
TAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPCTMCAGALVLARVARLV
FGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVLARECAAPLEAFFARQR
LG
>Rv1262c HYPOTHETICAL HIT-LIKE PROTEIN
MPCVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLT
DTPPEALADMVAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLH
VLPPRNGDKLSVAKGMMLRRDPDREATGRILREALAQQDAAAQD
>Rv1026 CONSERVED HYPOTHETICAL PROTEIN
MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGVDA
TGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVFFA
MTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLGGG
STEIVLGEHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARRLVRERL
EPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSRVPGADL
LEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELRERAGID
QLTVSEHDILDGIALSLAG
>Rv0828c POSSIBLE DEAMINASE
MPAGMAGFRRWAQTNDPTAHAESLAIRAACTKLGTEHLVGTTLNVLAHPC
PMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQD
RRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG
>Rv3210c CONSERVED HYPOTHETICAL PROTEIN
MPSPSSADQVADSPRPRLPADHPGVNELFALLAYGEVAAFYRLTDEARMA
PDLRGRISMASMAAAEMGHYELLRNALERRGVDVVSAMSKYTSALENYHR
LTTPSTWLEALVKTYVADALAADLYLEIADGLPDEVADVVRAALSETGHS
QFVVAEVRAAVTASGKQRSRLALWSRRLLGEAITQAQLVLADHDELVDLV
VSGSGGLSQLGAFFDRLQQTHDQRMRELGLS
>Rv0759c CONSERVED HYPOTHETICAL PROTEIN
MAFLTIEPMTQGHTLVVPRAEIDHWQNVDPALFGRVMSVSQLIGKAVCRA
FSTQRAGMIIAGLEVPHLHIHVFPTRSLSDFGFANVDRNPSPGSLDEAQA
KIRAALAQLA
>Rv0787A CONSERVED HYPOTHETICAL PROTEIN
MARVVVHVMPKAEILDPQGQAIVGALGRLGHLGISDVRQGKRFELEVDDT
VDDTTLAEIAESLLANTVIEDWTISRDPQ
>Rv0496 CONSERVED HYPOTHETICAL PROTEIN
MVDAHRGGHPTPMSSTKATLRLAEATDSSGKITKRGADKLISTIDEFAKI
AISSGCAELMAFATSAVRDAENSEDVLSRVRKETGVELQALRGEDESRLT
FLAVRRWYGWSAGRILNLDIGGGSLEVSSGVDEEPEIALSLPLGAGRLTR
EWLPDDPPGRRRVAMLRDWLDAELAEPSVTVLEAGSPDLAVATSKTFRSL
ARLTGAAPSMAGPRVKRTLTANGLRQLIAFISRMTAVDRAELEGVSADRA
PQIVAGALVAEASMRALSIEAVEICPWALREGLILRKLDSEADGTALIES
SSVHTSVRAVGGQPADRNAANRSRGSKP
>Rv3114 CONSERVED HYPOTHETICAL PROTEIN
MVAARLPFGWSADSGVTADIIEAAMELAIDTARHATAPFGAALLDVTTLR
AFSGGNTYFESGDRFAHAETNVLRAAMSTLPELSNHVLISTAEPCPMCAA
ASVLSGVRAIIFGTSIETLIQCGWFQIRISASDVVAASTRPTRPSVYSGF
LSHKTDLLYRNSENRRAMNPWTDPSH
>Rv2492 HYPOTHETICAL PROTEIN
MSRRIINEFGVQIYGATIGDTWAGLVRAVLDLGSQCFDEDRERIALSNVR
IKSSVQNYPDLTIEEHCNSAQLKAMLDFMFNTDTMEDIDVVKSFSRGAKS
YHRRIKEGRMIEFVIERLSLIPESKKAVVVFPTYEDYAAVMRNHRDDYLP
CLVSIQFRLLPDGKDYVFHTTFYSRSMDAWQKGHGNLLSIAKLSDWVREN
VSARIGRKIMLGPLDGMICDVHIYKETYAEACKRLANLDLRRTQFDAVRN
>Rv2613c CONSERVED HYPOTHETICAL PROTEIN
MSDEDRTDRATEDHTIFDRGVGQRDQLQRLWTPYRMNYLAEAPVKRDPNS
SASPAQPFTEIPQLSDEEGLVVARGKLVYAVLNLYPYNPGHLMVVPYRRV
SELEDLTDLESAELMAFTQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAE
HLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWARQP
>Rv3313c add, PROBABLE ADENOSINE DEAMINASE ADD (ADENOSINE AMINOHYDROLASE)
MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDA
LASWFRTQSHSGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSV
VYAEVRFAPELHISCGLSFDDVVDTVLTGFAAGEKACAADGQPITVRCLV
TAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRD
HNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADGGFQL
GRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD
NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIID
EVIKPRFAALMGHSE
>Rv0733 adk, PROBABLE ADENYLATE KINASE ADK (ATP-AMP TRANSPHOSPHORYLASE)
MRVLLLGPPGAGKGTQAVKLAEKLGIPQISTGELFRRNIEEGTKLGVEAK
RYLDAGDLVPSDLTNELVDDRLNNPDAANGFILDGYPRSVEQAKALHEML
ERRGTDIDAVLEFRVSEEVLLERLKGRGRADDTDDVILNRMKVYRDETAP
LLEYYRDQLKTVDAVGTMDEVFARALRALGK
>Rv1317c alkA, PROBABLE ADA REGULATORY PROTEIN ALKA (Regulatory protein of adaptative response) (Methylated-DNA--protein-cysteine methyltransferase) (O-6-methylguani
MHDDFERCYRAIQSKDARFDGWFVVAVLTTGVYCRPSCPVRPPFARNVRF
LPTAAAAQGEGFRACKRCRPDASPGSPEWNVRSDVVARAMRLIADGTVDR
DGVSGLAAQLGYTIRQLERLLQAVVGAGPLALARAQRMQTARVLIETTNL
PFGDVAFAAGFSSIRQFNDTVRLACDGTPTALRARAAARFESATASAGTV
SLRLPVRAPFAFEGVFGHLAATAVPGCEEVRDGAYRRTLRLPWGNGIVSL
TPAPDHVRCLLVLDDFRDLMTATARCRRLLDLDADPEAIVEALGADPDLR
AVVGKAPGQRIPRTVDEAEFAVRAVLAQQVSTKAASTHAGRLVAAYGRPV
HDRHGALTHTFPSIEQLAEIDPGHLAVPKARQRTINALVASLADKSLVLD
AGCDWQRARGQLLALPGVGPWTAEVIAMRGLGDPDAFPASDLGLRLAAKK
LGLPAQRRALTVHSARWRPWRSYATQHLWTTLEHPVNQWPPQEKIA
>Rv2584c apt, ADENINE PHOSPHORIBOSYLTRANSFERASE APT (APRT) (AMP DIPHOSPHORYLASE) (AMP PYROPHOSPHORYLASE) (TRANSPHOSPHORIBOSIDASE)
MCHGGTWAGDYVLNVIATGLSLKARGKRRRQRWVDDGRVLALGESRRSSA
ISVADVVASLTRDVADFPVPGVEFKDLTPLFADRRGLAAVTEALADRASG
ADLVAGVDARGFLVAAAVATRLEVGVLAVRKGGKLPRPVLSEEYYRAYGA
ATLEILAEGIEVAGRRVVIIDDVLATGGTIGATRRLLERGGANVAGAAVV
VELAGLSGRAALAPLPVHSLSRL
>Rv1383 carA, PROBABLE CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN CARA (Carbamoyl-phosphate synthetase glutamine chain)
MSKAVLVLEDGRVFTGRPFGATGQALGEAVFSTGMSGYQETLTDPSYHRQ
IVVATAPQIGNTGWNGEDSESRGERIWVAGYAVRDPSPRASNWRATGTLE
DELIRQRIVGIAGIDTRAVVRHLRSRGSMKAGVFSDGALAEPADLIARVR
AQQSMLGADLAGEVSTAEPYVVEPDGPPGVSRFTVAALDLGIKTNTPRNF
ARRGIRCHVLPASTTFEQIAELNPHGVFLSNGPGDPATADHVVALTREVL
GAGIPLFGICFGNQILGRALGLSTYKMVFGHRGINIPVVDHATGRVAVTA
QNHGFALQGEAGQSFATPFGPAVVSHTCANDGVVEGVKLVDGRAFSVQYH
PEAAAGPHDAEYLFDQFVELMAGEGR
>Rv1384 carB, PROBABLE CARBAMOYL-PHOSPHATE SYNTHASE LARGE CHAIN CARB (Carbamoyl-phosphate synthetase ammonia chain)
MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSN
PATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTA
LNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESAR
SRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAG
LAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTG
DSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRL
IVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPA
CFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALG
KVMRSLETTRAGFWTAPDPDGGIEEALTRLRTPAEGRLYDIELALRLGAT
VERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSDH
QIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSYE
LDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAGF
ETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGVA
GVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAAG
LPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQG
YITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGGIMEHIEEAG
IHSGDSACALPPVTLGRSDIAKVRKATEAIAHGIGVVGLLNVQYALKDDV
LYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRAEGLLAVT
GDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKSTGEVMGID
RDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRLADLGFRV
LATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAGEVNMVIN
TPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAGIRGDIGV
RSLQELHRVIGGVER
>Rv3315c cdd, PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE)
MPDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVS
YGLTLCAECAVVCALHSTGGGRLLALACVDGHGSVLMPCGRCRQVLLEHG
GSELLIDHPVRPRRLGDLLPDAFGLDDLPRERR
>Rv1712 cmk, Probable Cytidylate kinase cmk (CMP kinase) (Cytidine monophosphate kinase) (CK)
MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLR
AGADPSDIAAVETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRA
VSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLT
ASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGD
AVIVDTSDMTEAEVVAHLLELVTRRSEAVR
>Rv0321 dcd, PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE)
MLLSDRDLRAEISSGRLGIDPFDDTLVQPSSIDVRLDCLFRVFNNTRYTH
IDPAKQQDELTSLVQPVDGEPFVLHPGEFVLGSTLELFTLPDNLAGRLEG
KSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLC
MLRLTSPSEHPYGSSRAGSKYQGQRGPTPSRSYQNFIRST
>Rv3314c deoA, PROBABLE THYMIDINE PHOSPHORYLASE DEOA (TDRPASE) (PYRIMIDINE PHOSPHORYLASE)
MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAI
VWRGMDRGEIARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPL
VPVVAACGGAVPQASGRGLGHTGGTLDKLESITGFTANLSNQRVREQLCD
VGAAIFAAGQLAPADAKLYALRDITGTVESLPLIASSIMSKKLAEGAGAL
VLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNCPLGRT
VGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD
GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLA
AWRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGA
ARAELAGGWSIRDSPPQVRPLIVDRIV
>Rv0478 deoC, PROBABLE DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOC (PHOSPHODEOXYRIBOALDOLASE) (DEOXYRIBOALDOLASE)
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMV
PVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGA
ALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAA
EDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADA
VAMLNAGATRLGLSGTRAVLDGLS
>Rv3307 deoD, PROBABLE PURINE NUCLEOSIDE PHOSPHORYLASE DEOD (INOSINE PHOSPHORYLASE) (PNP)
MADPRPDPDELARRAAQVIADRTGIGEHDVAVVLGSGWLPAVAALGSPTT
VLPQAELPGFVPPTAAGHAGELLSVPIGAHRVLVLAGRIHAYEGHDLRYV
VHPVRAARAAGAQIMVLTNAAGGLRADLQVGQPVLISDHLNLTARSPLVG
GEFVDLTDAYSPRLRELARQSDPQLAEGVYAGLPGPHYETPAEIRMLQTL
GADLVGMSTVHETIAARAAGAEVLGVSLVTNLAAGITGEPLSHAEVLAAG
AASATRMGALLADVIARF
>Rv2344c dgt, PROBABLE DEOXYGUANOSINE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DGT (DGTPASE) (DGTP TRIPHOSPHOHYDROLASE)
MSASEHDPYDDFDRQRRVAEAPKTAGLPGTEGQYRSDFARDRARVLHSAA
LRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELA
GLAHDIGHPPYGHNGERALDEVAASHGGFEGNAQNFRILTSLEPKVVDAQ
GLSAGLNLTRASLDAVTKYPWMRGDGLGSQRRKFGFYDDDRESAVWVRQG
APPERACLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLAAEEDAAALA
RLGEREFSRVSADELMAAARRLSRLPVVAAVGKYDATLSASVALKRLTSE
LVGRFASAAIATTRAAAGPGPLVRFRADLQVPDLVRAEVAVLKILALQFI
MSDPRHLETQARQRERIHRVAHRLYSGAPQTLDPVYAAAFNTAADDAARL
RVVVDQIASYTEGRLERIDADQLGVSRNALD
>Rv2697c dut, PROBABLE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DUT (DUTPASE) (DUTP PYROPHOSPHATASE) (DEOXYURIDINE 5'-TRIPHOSPHATASE) (DUTP DIPHOSPHATASE) (
MSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVA
VAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPA
APIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGG
HASL
>Rv1389 gmk, PROBABLE GUANYLATE KINASE GMK
MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNLHF
SVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHRSG
TLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDLQA
RLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVSLL
VGTAPGSP
>Rv3396c guaA, PROBABLE GMP SYNTHASE [GLUTAMINE-HYDROLYZING] GUAA (GLUTAMINE AMIDOTRANSFERASE) (GMP SYNTHETASE)
MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASI
EEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQAMA
QALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPD
GFDVVASSAGAPVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFA
GLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRAIG
DRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVS
APEGKRKIIGRQFIRAFEGAVRDVLDGKTAEFLVQGTLYPDVVESGGGSG
TANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQ
PFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQIWQCPVVL
LADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEVLERISTRI
TNEVAEVNRVVLDITSKPPATIEWE
>Rv3410c guaB3, PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB3 (IMP DEHYDROGENASE) (INOSINIC ACID DEHYDROGENASE) (INOSINATE DEHYDROGENASE) (IMP OXIDOREDUCTASE)
MVEIGMGRTARRTYELSEISIVPSRRTRSSKDVSTAWQLDAYRFEIPVVA
HPTDALVSPEFAIELGRLGGLGVLNGEGLIGRHLDVEAKIAQLLEAAAAD
PEPSTAIRLLQELHAAPLNPDLLGAAVARIREAGVTTAVRVSPQNAQWLT
PVLVAAGIDLLVIQGTIVSAERVASDGEPLNLKTFISELDIPVVAGGVLD
HRTALHLMRTGAAGVIVGYGSTQGVTTTDEVLGISVPMATAIADAAAARR
DYLDETGGRYVHVLADGDIHTSGELAKAIACGADAVVLGTPLAESAEALG
EGWFWPAAAAHPSLPRGALLQIAVGERPPLARVLGGPSDDPFGGLNLVGG
LRRSMAKAGYCDLKEFQKVGLTVGG
>Rv3624c hpt, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HPT (HGPRT) (HGPRTase) (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE) (IMP PYROPHOSPHORYLASE) (IMP DIPHOSPHOR
MTPALVVGPAAWHAVHVTQSSSAITPGQTAELYPGDIKSVLLTAEQIQAR
IAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFE
FMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSR
NLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDER
YRDLSYIGTLDPRVYQ
>Rv3393 iunH, PROBABLE NUCLEOSIDE HYDROLASE IUNH (PURINE NUCLEOSIDASE)
MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLS
LLELCGAADIPVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTD
YDATTAWIAAAHSHAGDLIGLVTGPLTNLALALRAEPALPRLLRRLVIMG
GMFDGQPITEWNIRVDPEAASEVFTAWAGQRQLPIVCGLDLTRRVAMTPD
ILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAM
DPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER
IGRFARRT
>Rv1921c lppF, PROBABLE CONSERVED LIPOPROTEIN LPPF
MVRLIPSLLAMATVLGGVIGCSAHQPPTPASGCRQLDAFLKWHHGVREFL
QSAIDANSRCTGTADGSARKVAIFDWDNTVVKNDIGYATNYYMLQHSLVL
QPANQDWHAASRYLTDAAANALSVACGKVVPAGKPLPTGSNALCANEILS
LLDGETTTGQPAFVGNNVRRLAGPYAWSNALSAGYTAEELAGFADQAKKQ
NLAADVGATQQVGTQQVDGYIRVYPQMKDLIGTLQAHGIDTWVVSASPEP
IVKVWAGEVGLDDQHVVGVRSVADQSGKLTAHLVGCGGVRDGDDSVMTYL
DGKRCWANQVIFGVTGPQAFNQLAADRRQVLAAGDSNSDATFVGDATVVS
LVINRNQDDLMCRAYDGLFTRGGKWAINPMFIDPLPQHAPYVCGEAFINP
DGSKQPVLRNDGTPIPDQVDSVF
>Rv0091 mtn, PROBABLE BIFUNCTIONAL MTA/SAH NUCLEOSIDASE MTN: 5'-METHYLTHIOADENOSINE NUCLEOSIDASE (METHYLTHIOADENOSINE METHYLTHIORIBOHYDROLASE) + S-ADENOSYLHOMOCYST
MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAA
GMGKVNTGLTATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQH
DFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAP
LSTAAGGGGRQPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGA
VAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAASSARVLLRLLP
VLTAC
>Rv2445c ndkA, PROBABLE NUCLEOSIDE DIPHOSPHATE KINASE NDKA (NDK) (NDP KINASE) (NUCLEOSIDE-2-P KINASE)
MTERTLVLIKPDGIERQLIGEIISRIERKGLTIAALQLRTVSAELASQHY
AEHEGKPFFGSLLEFITSGPVVAAIVEGTRAIAAVRQLAGGTDPVQAAAP
GTIRGDFALETQFNLVHGSDSAESAQREIALWFPGA
>Rv0233 nrdB, PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDB (RIBONUCLEOTIDE REDUCTASE SMALL CHAIN)
MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRADWEKLS
DDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFE
EAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADP
SPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGD
DERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG
DQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDT
FADEDRRTLAAASA
>Rv3051c nrdE, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN)
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENY
YEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKR
YLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKKQ
RGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPI
KNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLD
TKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVP
FADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDT
VNRANPIDGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLN
IAKTMDSPDFAQTIEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQ
MNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGTHFK
GFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIPTQDDWRRLKE
SVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVY
YPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTA
TTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
>Rv1981c nrdF1, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF1 (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN)
MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQT
LSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDAVTPHEEAVLTNMAFM
ESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDA
LKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGY
YIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYAHDLYDELGWT
DDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFF
SGSGSSYVMGTHQPTTDTDWDF
>Rv3048c nrdF2, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF2 (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN)
MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSW
GTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIA
FMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQRKAEIVLQYYRGD
EPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVH
GYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVG
LTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHD
FFSGSGSSYVIGKAVVTEDDDWDF
>Rv3052c nrdI, PROBABLE NRDI PROTEIN
MDIAGRSLVYFSSVSENTHRFVQKLGIPATRIPLHGRIEVDEPYVLILPT
YGGGRANPGLDAGGYVPKQVIAFLNNDHNRAQLRGVIAAGNTNFGAEFCY
AGDVVSRKCSVPYLYRFELMGTEDDVAAVRTGLAEFWKEQTCHQPSLQSL
>Rv0570 nrdZ, PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (LARGE SUBUNIT) NRDZ (RIBONUCLEOTIDE REDUCTASE)
MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAV
ADALGRGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQRRAELRTAKAL
LGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDRSARCVAAAED
QYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIED
SLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFL
RLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNL
SVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGD
PGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLA
DGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGLGVMG
LAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAFPAFT
DSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRH
LLEVNPCFDRLARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAA
EIAPQWHLRMQAAVQRHVEAAVSKTVNLPATATVDDVRAIYVAAWKAKVK
GITVYRYGSREGQVLSYAAPKPLLAQADTEFSGGCAGRSCEF
>Rv0535 pnp, PROBABLE 5'-METHYLTHIOADENOSINE PHOSPHORYLASE PNP (MTA PHOSPHORYLASE)
MHNNGRMLGVIGGSGFYTFFGSDTRTVNSDTPYGQPSAPITIGTIGVHDV
AFLPRHGAHHQYSAHAVPYRANMWALRALGVRRVFGPCAVGSLDPELEPG
AVVVPDQLVDRTSGRADTYFDFGGVHAAFADPYCPTLRAAVTGLPGVVDG
GTMVVIQGPRFSTRAESQWFAAAGCNLVNMTGYPEAVLARELELCYAAIA
LVTDVDAGVAAGDGVKAADVFAAFGENIELLKRLVRAAIDRVADERTCTH
CQHHAGVPLPFELP
>Rv1017c prsA, PROBABLE RIBOSE-PHOSPHATE PYROPHOSPHOKINASE PRSA (Phosphoribosyl pyrophosphate synthetase) (PRPP synthetase)
MSHDWTDNRKNLMLFAGRAHPELAEQVAKELDVHVTSQDAREFANGEIFV
RFHESVRGCDAFVLQSCPAPVNRWLMEQLIMIDALKRGSAKRITAVMPFY
PYARQDKKHRGREPISARLIADLLKTAGADRIVTVDLHTDQIQGFFDGPV
DHMRGQNLLTGYIRDNYPDGNMVVVSPDSGRVRIAEKWADALGGVPLAFI
HKTRDPRVPNQVVSNRVVGDVAGRTCVLIDDMIDTGGTIAGAVALLHNDG
AGDVIIAATHGVLSDPAAQRLASCGAREVIVTNTLPIGEDKRFPQLTVLS
IAPLLASTIRAVFENGSVTGLFDGDA
>Rv0357c purA, PROBABLE ADENYLOSUCCINATE SYNTHETASE PURA (IMP--ASPARTATE LIGASE) (ADSS) (AMPSASE)
MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGEN
FALHLIPSGVLTPGVTNVIGNGVVIDPGVLLNELRGLQDRGVDTAKLLIS
ADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVAD
VLDPEQLTHKVEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHR
IADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAV
GSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVT
TGRRRRCGWFDAVIARYAARVNGITDYFLTKLDVLSSLESVPVCVGYEID
GRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLR
LEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP
>Rv0777 purB, PROBABLE ADENYLOSUCCINATE LYASE PURB (ADENYLOSUCCINASE) (ASL) (ASASE)
MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADS
VLADYERVVDDVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTS
RDLTENVEQLQIRRSLEVIFAHGVAAVARLAERAVSYRDLIMAGRSHNVA
AQATTLGKRFASAAQEMMIALRRLRELIDRYPLRGIKGPMGTGQDMLDLL
GGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVVSALVQLGAGP
SSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEF
GAYPAVIGRELDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATAL
AMREHGAEPDLLDRLAADPRLTLGRDALEAALADKKAFAGAAGDQVDDVV
AMVDALVSRYPDAAKYTPGAIL
>Rv0780 purC, PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE PURC (SAICAR SYNTHETASE)
MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKG
RVLTAMSAFFFGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVEC
VARGYLTGSGLLDYQATGKVCGIALPPGLVEASRFATPLFTPATKAALGD
HDENISFDRVVEMVGALRANQLRDRTLQTYVQAADHALTRGIIIADTKFE
FGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDKQFVRSWLTGS
ESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA
>Rv0772 purD, PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE) (5'-PHOSPHORIB
MRVLVIGSGAREHALLLALGKDPQVSGLIVAPGNAGTARIAEQHDVDITS
AEAVVALAREVGADMVVIGPEVPLVLGVADAVRAAGIVCFGPGKDAARIE
GSKAFAKDVMAAAGVRTANSEIVDSPAHLDAALDRFGPPAGDPAWVVKDD
RLAAGKGVVVTADRDVARAHGAALLEAGHPVLLESYLDGPEVSLFCVVDR
TVVVPLLPAQDFKRVGEDDTGLNTGGMGAYAPLPWLPDNIYREVVSRIVE
PVAAELVRRGSSFCGLLYVGLAITARGPAVVEFNCRFGDPETQAVLALLE
SPLGQLLHAAATGKLADFGELRWRDGVAVTVVLAAENYPGRPRVGDVVVG
SEAEGVLHAGTTRRDDGAIVSSGGRVLSVVGTGADLSAARAHAYEILSSI
RLPGGHFRSDIGLRAAEGKISV
>Rv3275c purE, PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT PURE (AIR CARBOXYLASE) (AIRC)
MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHRTPEA
MFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDG
LDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQLRARIVAFQ
DRLADVVAAKDAELQRLAGKLTRD
>Rv0808 purF, AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE)
MAVDSDYVTDRAAGSRQTVTGQQPEQDLNSPREECGVFGVWAPGEDVAKL
TYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMQGH
VAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARA
RDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFC
LTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDI
EPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAARV
EIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGVPYGQGLMKNAYVG
RTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRM
LREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVR
HAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYPIELPRETALGKNV
IEHMLANAARGAALGELAADDEVPVGR
>Rv0957 purH, PROBABLE BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH: PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE (AICAR TRANSFORMYLASE) (5'-PHOSPHORI
MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADT
GIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGI
EAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAV
VTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYDIAVASWMQQTL
APEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLAQAEQ
LHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALD
VLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTL
ATGSPADPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDA
ARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGVTAVVHPGGSVRDE
EVTEAAAKAGVTLYLTGARHFAH
>Rv3276c purK, PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE SUBUNIT PURK (AIR CARBOXYLASE) (AIRC)
MMAVASSRTPAVTSFIAPLVAMVGGGQLARMTHQAAIALGQNLRVLVTSA
DDPAAQVTPNVVIGSHTDLAALRRVAAGADVLTFDHEHVPNELLEKLVAD
GVNVAPSPQALVHAQDKLVMRQRLAAAGVAVPRYAGIKDPDEIDVFAARV
DAPIVVKAVRGGYDGRGVRMARDVADARDFARECLADGVAVLVEERVDLR
RELSALVARSPFGQGAAWPVVQTVQRDGTCVLVIAPAPALPDDLATAAQR
LALQLADELGVVGVLAVELFETTDGALLVNELAMRPHNSGHWTIDGARTS
QFEQHLRAVLDYPLGDSDAVVPVTVMANVLGAAQPPAMSVDERLHHLFAR
MPDARVHLYGKAERPGRKVGHINFLGSDVAQLCERAELAAHWLSHGRWTD
GWDPHRASDDAVGVPPACGGRSDEEERRL
>Rv0803 purL, PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II PURL (FGAM SYNTHASE II)
MLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVM
WSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTF
KVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP
DTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDPCYAGNPLVNALCVGVLR
QEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPS
VQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGG
MTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEV
LATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDA
LNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTV
LAEHADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNV
AVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGN
VSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTR
DEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDL
SEGGLAQAIVESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTE
ESRFRGMCEARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLP
RYFG
>Rv0809 purM, PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE PURM (AIRS) (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE) (AIR SYNTHASE)
MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRG
GLGGFAGLFTLRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAM
VVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIADGCMRAGCALLGG
ETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSSGLH
SNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAA
ETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGR
VRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGK
QGPRAKLVGQHPRF
>Rv0956 purN, PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN (GART) (GAR TRANSFORMYLASE) (5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE)
MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARVVAVGVDREC
RAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPDLVVSAGFMR
ILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKVTGATVHLVD
AGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAVAALATHGVT
VVGRTATMGRKVTIG
>Rv0788 purQ, PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE I PURG (FGAM SYNTHASE I)
MTARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPG
GFSYGDYLRAGAIARFAPVMDEVVAAADRGMPVLGICNGFQVLCEAGLLP
GALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVA
PEKVLDELEGEGRVVFRYHDNVNGSLRDIAGICSANGRVVGLMPHPEHAI
EALTGPSDDGLGLFYSALDAVLTG
>Rv0389 purT, PROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 PURT (GART 2) (GAR TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE 2) (FORMATE-D
MIDGWTEEQHEPTVRHERPAAPQDVRRVMLLGSAEPSRELAIALQGLGAE
VIAVDGYVGAPAHRIADQSVVVTMTDAEELTAVIRRLQPDFLVTVTAAVS
VDALDAVEQADGECTELVPNARAVRCTADREGLRRLAADQLGLPTAPFWF
VGSLGELQAVAVHAGFPLLVSPVAGVAGQGSSVVAGPNEVEPAWQRAAGH
QVQPQTGGVSPRVCAESVVEIEFLVTMIVVCSQGPNGPLIEFCAPIGHRD
ADAGELESWQPQKLSTAALDAAKSIAARIVKALGGRGVFGVELMINGDEV
YFADVTVCPAGSAWVTVRSQRLSVFELQARAILGLAVDTLMISPGAARVI
NPDHTAGRAAVGAAPPADALTGALGVPESDVVIFGRGLGVALATAPEVAI
ARERAREVASRLNVPDSRE
>Rv2964 purU, PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE)
MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTF
LARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVA
DKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIA
NHPDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYM
QILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYV
TEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQDRV
IVHHNQTIVF
>Rv1380 pyrB, PROBABLE ASPARTATE CARBAMOYLTRANSFERASE PYRB (ATCase) (Aspartate transcarbamylase)
MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTM
FYENSTRTRVSFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAG
ADALIIRHPASGAAHLLAQWTGAHNDGPAVINAGDGTHEHPTQALLDALT
IRQRLGGIEGRRIVIVGDILHSRVARSNVMLLDTLGAEVVLVAPPTLLPV
GVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSVRYGL
TERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRM
AVLFHVLVGAQDAGKEGAA
>Rv1381 pyrC, PROBABLE DIHYDROOROTASE PYRC (DHOase)
MSVLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLL
PGFVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPV
VTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMNAGAAQVRMFSD
DGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAVAHEGPMAARLG
LAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGIS
ITAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDC
VATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIA
RVMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSAN
TPFESMSLPATVTATLLRGKVTARDGKIRA
>Rv2139 pyrD, Probable dihydroorotate dehydrogenase PyrD
MYPLVRRLLFLIPPEHAHKLVFAVLRGVAAVAPVRRLLRRLLGPTDPVLA
STVFGVRFPAPLGLAAGFDKDGTALSSWGAMGFGYAEIGTVTAHPQPGNP
APRLFRLADDRALLNRMGFNNHGARALAIRLARHRPEIPIGVNIGKTKKT
PAGDAVNDYRASARMVGPLASYLVVNVSSPNTPGLRDLQAVESLRPILSA
VRAETSTPVLVKIAPDLSDSDLDDIADLAVELDLAGIVATNTTVSRDGLT
TPGVDRLGPGGISGPPLAQRAVQVLRRLYDRVGDRLALISVGGIETADDA
WERITAGASLLQGYTGFIYGGERWAKDIHEGIARRLHDGGFGSLHEAVGS
ARRRQPS
>Rv0382c pyrE, PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE)
MAGPDRAELAELVRRLSVVHGRVTLSSGREADYYVDLRRATLHHRASALI
GRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSAKAH
GMQRLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVV
DRATGAAEAIEAEGLRYRSVLGLADLGLD
>Rv1385 pyrF, PROBABLE OROTIDINE 5'-PHOSPHATE DECARBOXYLASE PYRF (OMP decarboxylase) (OMPdecase)
MTGFGLRLAEAKARRGPLCLGIDPHPELLRGWDLATTADGLAAFCDICVR
AFADFAVVKPQVAFFESYGAAGFAVLERTIAELRAADVLVLADAKRGDIG
ATMSAYATAWVGDSPLAADAVTASPYLGFGSLRPLLEVAAAHGRGVFVLA
ATSNPEGAAVQNAAADGRSVAQLVVDQVGAANEAAGPGPGSIGVVVGATA
PQAPDLSAFTGPVLVPGVGVQGGRPEALGGLGGAASSQLLPAVAREVLRA
GPGVPELRAAGERMRDAVAYLAAV
>Rv1699 pyrG, Probable CTP synthase PyrG
MRKHPQTATKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPY
LNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLPGSANVTTGQ
VYSTVIAKERRGEYLGDTVQVIPHITDEIKRRILAMAQPDADGNRPDVVI
TEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSLVPYLAPSGELKT
KPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVIST
PDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHE
TVRIALVGKYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSG
AAAALGDVHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIV
IEAARSVGLTNANSAEFDPDTPDPVIATMPDQEEIVAGEADLGGTMRLGS
YPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDKIAESGLRFSGTSP
DGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAIDYKA
GELLPVEIPEIPEHTPNGSSHRDGVGQPLPEPASRG
>Rv2883c pyrH, PROBABLE URIDYLATE KINASE PYRH (UK) (URIDINE MONOPHOSPHATE KINASE) (UMP KINASE)
MTEPDVAGAPASKPEPASTGAASAAQLSGYSRVLLKLGGEMFGGGQVGLD
PDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGMERTRSDYMG
MLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGR
VVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVFAEDPRVNPE
AELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLLTDGNIARAV
RGEKIGTLVTT
>Rv1379 pyrR, PROBABLE PYRIMIDINE OPERON REGULATORY PROTEIN PYRR
MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRV
VLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPL
ASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLV
DRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR
>Rv2764c thyA, PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)
MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKV
HFKSVAYELLWFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRS
WPAPSGEHIDQISAALDLLRTDPDSRRIIVSAWNVGEIERMALPPCHAFF
QFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFI
WTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTYEDIVVKN
YDPHPAIKAPVAV
>Rv2754c thyX, PROBABLE THYMIDYLATE SYNTHASE THYX (TS) (TSase)
MAETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKP
NPKTATNAGYLRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFS
YSQLSQRYVPEKDSRVVVPPGMEDDADLRHILTEAADAARATYSELLAKL
EAKFADQPNAILRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRA
SEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEVATSPLATEA
>Rv3247c tmk, PROBABLE THYMIDYLATE KINASE TMK (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK)
MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAE
ALHGEHGDLASSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASN
AAYSAARLHENAAGKAAAWVQRIEFARLGLPKPDWQVLLAVSAELAGERS
RGRAQRDPGRARDNYERDAELQQRTGAVYAELAAQGWGGRWLVVGADVDP
GRLAATLAPPDVPS
>Rv3309c upp, PROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP PYROPHOSPHORYLASE) (UPRTASE) (UMP DIPHOSPHORYLASE)
MQVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCE
PVPIRTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGV
ARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGA
ADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAG
DRQFGPR